Proceedings on Engineering Sciences | 2026
Authors: Kadhim M.J.; Ali Z.A.U.A.; Alqaraghuli H.A.; Obaid N.M.
DOI: 10.24874/PES08.01B.015
Journal: Proceedings on Engineering Sciences
Year: 2026
Publisher: Faculty of Engineering, University of Kragujevac
Document Type: Article
Open Access: All Open Access; Gold Open Access; Green Open Access
Cited by: 0
Asthma continues to be a major health issue worldwide, with an increasing prevalence impacting over 300 million people and contributing significantly to morbidity and mortality. This study investigates the role of interleukin-17 (IL-17) in different asthma phenotypes, focusing on its potential as a biomarker for disease severity and control. The primary aim was to measure & compare the serum levels of IL-17 in asthmatic patients with healthy controls and to explore correlation of IL-17 levels with other inflammatory markers such as IgE, C-reactive protein (CRP), and eosinophil count. Additionally, the study sought to determine the relationship between IL-17 levels and asthma control status. The study encompassed 140 participants, divided equally between asthmatic cases and healthy controls, showing IL-17 levels were elevated in asthma patients though not reaching statistical significance. A clear association was observed between elevated IL-17 levels and other biomarkers with deteriorating control of asthma symptoms. While the direct correlation between serum IL-17 levels and asthma severity was not statistically significant, the study indicates the potential of IL-17 to be a contributing factor in severe asthma cases. Further studies are needed to confirm these findings and assess IL-17’s utility in clinical practice for asthma diagnosis and treatment. © 2026 Published by Faculty of Engineering.
Asthma; Asthma Control; Biomarkers; IL-17; Inflammation; Phenotypes