Journal of Rawalpindi Medical College | 2026
Authors: Ali L.; Shahid A.; Faisal F.; Usama S.M.; Nasir M.; Kayani R.M.
DOI: 10.37939/jrmc.v30i1.3154
Journal: Journal of Rawalpindi Medical College
Year: 2026
Publisher: Rawalpindi Medical University
Document Type: Article
Open Access: All Open Access; Gold Open Access
Cited by: 0
Objective: This study aimed to identify the frequency and associated factors of multidrug resistance-causing UTI in women presenting to the urology department of Shifa International Hospital, Islamabad. Methods: This cross-sectional study was conducted from July to September 2025 at the Urology Department of Shifa International Hospital, Islamabad, using a sample of 317 cases. Non-probability consecutive sampling was used to select the samples. A structured questionnaire was used to collect data, including administrative details, sociodemographic information, clinical status, and urine culture results. Data were entered and analysed using the Statistical Package for the Social Sciences (SPSS) version 24. Bivariate analysis was performed for demographic variables and resistance patterns. Results: Out of 317 cases of culture-positive urinary tract infection, the mean age of the respondents was 55.85 years. Escherichia coli was the most common organism (225 [70.98%]), followed by Klebsiella pneumoniae (43 [13.56%]). Multidrug resistance was observed in 218 (68.7%) of the cases. Significant associations were found between marital status, comorbid conditions, presence of blood in urine, antibiotic use history, and type of infecting microbe. Conclusion: Antimicrobial resistance was observed in 218 (68.7%) women with culture-positive urinary tract infections. Regarding the microbe, the most common organism was Escherichia coli 225 (70.98%). Significant associated factors with MDR included marital status, diabetes, hypertension, frequent antibiotic use, and the presence of blood in urine and gram-negative organisms. To prevent the emergence of resistance and encourage the responsible consumption of antibiotics, the results highlight the critical need for enhanced antibiotic stewardship initiatives. © 2026 Ali et al.
Drug Resistance; Females; Microbial; Urinary Tract Infections